It also known as time-lapse embryo monitoring, is a technique used in the field of assisted reproductive technology (ART) to assess the development and quality of embryos during in vitro fertilization (IVF). It involves capturing continuous images or videos of developing embryos at regular intervals without the need to remove them from the incubator. This provides a dynamic and detailed view of embryo development over time.
The embryos are placed in a specialized incubation system that incorporates a microscope and camera. The system maintains optimal culture conditions, including temperature, humidity, and gas composition.
The camera captures images or records videos of the embryos at pre-determined time intervals, typically every 5 to 20 minutes. The system may use different imaging modalities, such as bright-field or dark-field microscopy, to visualize the embryos.
The captured images or videos are analyze
d using specialized software. The software can track the development of individual embryos, identify specific developmental milestones, and assess the morphogenetic (timing and patterns) of embryo division and growth.
Time-lapse imaging provides additional information about embryo development compared to traditional methods. Embryologists can analyze the development and quality parameters of the embryos based on various criteria, such as the timing of cell divisions, synchronization of embryonic development, and morphological changes.
The time-lapse imaging data can aid in the selection of the most viable embryos for transfer or cryopreservation. Embryologists can assess the embryos’ developmental potential, selecting those that demonstrate normal and optimal growth patterns, as well as identifying any potential abnormalities or delays.
The ability to observe embryo development in real-time provides a more comprehensive assessment of embryo quality and development potential.
It allows for continuous monitoring without the need to disturb the embryos by removing them from the incubator.
The additional information provided by this technique can assist embryologists in making more informed decisions about embryo selection, potentially improving pregnancy rates.
It’s important to note that while this imaging can provide valuable information, it is not a guarantee of success. The ultimate viability and success of an embryo depend on various factors, including genetic health, chromosomal normality, and other individual factors.
The use of this technique may vary between fertility clinics and depends on their available technology and protocols. Consulting with a fertility specialist or embryologist can provide more specific information about the implementation of this technique in your particular IVF treatment.